Characterisation of recombinant glycosylation variants of insulin-like growth factor binding protein-3
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چکیده
منابع مشابه
Characterisation of recombinant glycosylation variants of insulin-like growth factor binding protein-3.
There are three potential N-glycosylation sites in the non-conserved central region of the insulin-like growth factor binding protein-3 (IGFBP-3) sequence (N89AS, N109AS, N172FS). IGFBP-3 exists as two glycoforms which reduce to a single form on enzymatic deglycosylation. To determine the functional significance of the carbohydrate chains, the N-glycosylation sites were mutated singly and in co...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 1999
ISSN: 0022-0795,1479-6805
DOI: 10.1677/joe.0.1600379